姓名：毛国涛
性别：男
职称：副教授
邮编：450002
通信地址：郑州市文化路95号 4008云顶国际集团
邮箱地址：maoguotao@henau.edu.cn
2016.07-至今 4008云顶国际集团，讲师、校聘副教授（青年英才）
2011.09-2016.07 中国科学院生物物理研究所，博士学位
2007.09-2011.07 吉林大学4008云顶国际集团，学士学位
基因工程、酶工程
从事微生物酶工程研究工作，聚焦木质纤维素等资源化利用相关酶的挖掘、结构与功能分析、改造及应用方面的研究
15. Guotao Mao, Ming Song, Jin Yu, Junhan Lin, Zhanhe Wang, Zengping Su, Hui Xie, Hognsen Zhang*, Hongge Chen, Andong Song*, One-pot tailored synthesis of highly monodisperse β-1, 3-glucan from sucrose driven by an in vitro self-assembled dual-enzyme system via spy chemistry, Carbohydrate Polymers, 2025, 366: 123878.
14. Hongsen Zhang, Wenjing Li, Yufei Yang, Guotao Mao*, Fengqin Wang, Hui Xie, Zengping Su, Jingliang Xu, Andong Song*, Low-alkali assisted instant catapult steam explosion enhances enzymatic hydrolysis of corn stover by alleviating anti-enzymatic hydrolysis factors through lignin structural rearrangement, Polymers, 2025, 17: 3148.
13. Guotao Mao, Ming Song, Hao Li, Junhan Lin, Kai Wang, Qian Liu, Zengping Su, Hongsen Zhang, Lijuan Su, Hui Xie*, Andong Song*, Biochemical and structural characterization of a highly glucose-tolerant β-glucosidase from the termite Reticulitermes perilucifugus, International Journal of Molecular Sciences, 2025, 26: 3118.
12. Yuanyuan Zhang, Yapeng Li, Hui Lin, Guotao Mao, Xiang Long, Xinyu Liu, Hongge Chen*, Broadening the substrate specificity of cellobiose phosphorylase from Clostridium thermocellum for improved transformation of cellodextrin to starch, International Journal of Molecular Sciences, 2023, 24: 14452.
11. Yinling Gao, Fengqin Wang*, Xiaojuan Li, Guotao Mao, Hui Xie, Andong Song*, Júlio Cesar dos Santos, Zhanying Zhang, Tailored production of citric acid and mannitol by Yarrowia lipolytica from corn stover pretreated by glycerol-assisted instant catapult steam explosion, Industrial Crops and Products, 2022, 189: 115820.
10. 毛国涛, 王杰, 王凯, 王方园, 曹乐言, 张宏森, 宋安东*, 水生栖热菌漆酶TaLac的性质分析及对孔雀石绿染料的脱除, 生物技术通报, 2022, 38(4): 261-268.
9. Guotao Mao, Fangyuan Wang, Jie Wang, Pengyu Chen, Xiaodong Zhang, Hongsen Zhang, Zhimin Wang, Andong Song*, A sustainable approach for degradation and detoxification of malachite green by an engineered polyphenol oxidase at high temperature, Journal of Cleaner Production, 2021, 328: 129437.
8. Guotao Mao, Kai Wang, Fangyuan Wang, Hao Li, Hongsen Zhang, Hui Xie, Zhimin Wang, Fengqin Wang, Andong Song*, An engineered thermostable laccase with great ability to decolorize and detoxify malachite green, International Journal of Molecular Sciences, 2021, 22: 11755.
7. Hui Xie#, Zhimin Li#, Zhimin Wang, Guotao Mao, Hongsen Zhang, Fengqin Wang, Hongge Chen, Sen Yang, Yiu Fai Tsang, Su Shiung Lam*, Andong Song*, Zhanying Zhang, Instant Catapult Steam Explosion: A rapid technique for detoxification of aflatoxin-contaminated biomass for sustainable utilization as animal feed, Journal of Cleaner Production, 2020, 255: 120010.
6. 毛国涛, 刘茜, 王方园, 苏丽娟, 张宏森, 宋安东*, 近暗散白蚁β-葡萄糖苷酶RpBgl7的异源表达及酶学性质研究, 河南农业科学, 2020, 49(7): 68-74.
5. 毛国涛, 王园园, 李斌, 刘茜, 张宏森, 谢慧, 陈红歌, 宋安东*, 非洲栖热腔菌(Thermosipho africanus)纤维寡糖磷酸化酶的结晶及衍射分析, 河南农业大学学报, 2019, 53(3): 400-405.
4. Hui Xie, Dong Zhang, Guotao Mao, Fengqin Wang, Andong Song*, Availability of lignocellulose from forestry waste for use as a biofuel in China, 3 Biotech, 2018, 8(5): 234.
3. Yuanyuan Wu, Guotao Mao, Haiyan Fan, Andong Song, Yi-Heng Percival Zhang, Hongge Chen*, Biochemical properties of GH94 cellodextrin phosphorylase THA_1941 from a thermophilic eubacterium Thermosipho africanus TCF52B with cellobiose phosphorylase activity, Scientific Reports, 2017, 7, 017-05289.
2. Guotao Mao#, Yan Zhao#, Xusheng Kang, Zhijie Li, Yan Zhang, Xianping Wang, Fei Sun, Krishnan Sankaran, Xuejun Cai Zhang*, Crystal structure of E. coli lipoprotein diacylglyceryl transferase, Nature Communications, 2016, 7: 10198.
1. Yan Zhao#, Guotao Mao#, Min Liu, Laixing Zhang, Xianping Wang, Xuejun Cai Zhang*, Crystal Structure of the E. coli peptide transporter Ybgh, Structure, 2014, 22(8): 1152-1160.
7. 可基因编辑点击化学驱动的漆酶同步纯化与定向固定化及其在印染废水处理中的应用，河南省科技攻关项目，202601-202712，主持
6. 昆布聚糖的酶法制备体系构建及分子量调控，国家重点研发计划重点专项子课题， 202211-202710，主持
5. 高效特异降解黄曲霉毒素B1的CotA漆酶的定向重塑及应用，河南省科技研发计划联合基金（应用攻关类）项目，202310-202510，主持
4. 高热稳定性与葡萄糖耐受性β-葡萄糖苷酶的开发及其在秸秆类农业废弃物资源化中的应用，河南省科技攻关项目，202301-202412，主持
3. 双功能纤维二糖磷酸化酶TaCBP宽泛的底物特异性的结构基础研究，国家自然科学基金青年项目，201901-202112，主持
2. 新型DUF152家族漆酶的发掘及秸秆类木质纤维素高效酶解体系的构建，河南省科技攻关项目，201901-202012，主持
1. 纤维二糖磷酸化酶的结构与功能研究，河南农业大学青年英才项目，201704-202204，主持
4. 毛国涛，宋安东，高蕾，苏增平，田甜，谢慧，张宏森，高效降解黄曲霉毒素B1 的漆酶HcCotA 的分子及其应用， CN202510310558.8
3. 毛国涛，宋安东，宋明，林俊含，王湛贺，于金，陈红歌，苏增平，张宏森，谢慧，一种基于自组装体系从蔗糖合成特定聚合度的β-1,3-葡聚糖的体外双酶催化体系， CN202510462632.8
2. 毛国涛，宋安东，王方园，王杰，王风芹，谢慧，张宏森，细菌漆酶在降解有机染料中的应用，ZL202011406126.0
1. 毛国涛，宋安东，王方园，王杰，王风芹，谢慧，张宏森 ，一种Cblac-Mut8漆酶突变体，ZL202011399467.X
